Yes, because Avast cannot work properly if another antivirus programme is installed on the same system. Using two or more antivirus programmes can cause problems and may make the operating system unstable.
To uninstall a programme from your PC, go to Control Panel > Programmes > Uninstall a programme > Select the software you wish to uninstall > Click on Uninstall. Follow the instructions that appear on the screen.
When the software is uninstalled, Restart your PC Then install Avast.